- Description
- Specifications
Catalog #: HIV-154
Description:
HIV-1 gp120 CM Recombinant- is the external envelope protein, full-length 120 kDa, derived from the env. gene of HIV-1 and glycosylated with N-linked sugars and produced using baculovirus vectors in insect cells. The gp120CM stands for Chaing Mai from Clade E and is M-tropic meaning it binds to CCR5.
Purified under conditions that maintain the tertiary structure of the molecule.
Source:
Baculovirus, Insect Cells.
Purity:
Greater than 90.0% as determined by HPLC analysis and SDS-PAGE.
Formulation:
(311 µg/ml) 10mM Tris-Cl, pH-7.6, 150mM NaCl and 0.01% Triton N-101.
Stability:
Recombinant HIV -1 gp120 CM although stable at 4 °C for 3 weeks, should be stored desiccated below -18 °C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze-thaw cycles.
Physical Appearance:
Sterile filtered colorless clear solution.
References:
Title:Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability.
Publication:Zhang X, Yu J, Kuzontkoski PM, Zhu W, Li DY, et al. (2012) Slit2/Robo4 Signaling Modulates HIV-1 gp120-Induced Lymphatic Hyperpermeability. PLoS Pathog 8(1): e1002461. doi:10.1371/journal.ppat.1002461
Link:http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2Fjournal.ppat.1002461
