The purity and homogeneity of the protein preparation often plays a critical role in crystallography studies as it affects the quality and diffraction of the crystals obtained. Instead of wasting months trying to optimize your crystallization conditions, it may be easier and in fact smarter to know more about your protein itself. Characterization of your protein offers significant insight  and clues about your protein's primary, secondary, tertiary and quarternary structure. It can help you during new product development, screening and lead selection and save time and resources and can quicken the time to preclinical and clinical development stages.

The characterization of proteins is dependent on the biochemical, biophysical characteristics such as protein size, shape, amino acid sequence composition and physiochemical properties such as isoelectric point, molecular weight, relative hydrophobicity and spectral analysis.

We offer the following packages, but  if you don't find what you need, This email address is being protected from spambots. You need JavaScript enabled to view it. and we can customize the package that best suits your needs.

Package A - For Drug discovery: Determination of isoelectric point by IEF, amino acid composition and N-terminal sequencing, size-exclusion chromatography and SDS-Page characterization, liagand screening by Biacore.

Package B- For Crystallography: Peptide-mass determination (mass-spectrometry,MALDI-Tof ), dynamic and static light scattering, native gel electrophoresis and SEC (protein-protein interractions, homogeneity of the sample), Isoelectric focussing (pI),  and protein-ligand screening by Biacore, protein-DNA binding by fluorescence assays.

Package C - For antibody discovery: Western blotting, dot-blots, antibody-isotyping ELISA, Cell based bioassays.

Pricing : Depends on the number of parameters tested. Basic packages start from $ 400 and up.   For addition information and to request a quote please This email address is being protected from spambots. You need JavaScript enabled to view it..