- Description
- Specifications
Catalog #: HIV-101
Description:
HIV-1 envelope is an E.coli-derived recombinant protein that composes all of the reported immunogenic determinants found in gp41 and a small portion of gp120. The gene encoding this fusion protein was synthesized using codons optimized for E.coli expression and doesn't represent a linear HIV-1 envelope sequence. HIV-1 is a non-glycosylated, 233 amino acid polypeptide chain, having a molecular mass of 27275.88 dalton and pI=9.68. HIV-1 envelope protein spans the C-Terminus of gp120 and most of gp41. Superior diagnostic reagent for HIV-1 and HIV type-O detection. Detects all HIV-1 and HIV-type O infected individuals responding to envelope proteins.
Source:
Escherichia Coli.
Applications:
HIV-1 Envelope antigen is suitable for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
Purity:
Greater than 95.0% as determined by HPLC analysis and SDS-PAGE.
Formulation:
The HIV-1 contains 0.5X PBS & 6M urea.
Stability:
HIV-1 Envelope although stable at 4 °C for 1 week, should be stored below -18 °C.
Please prevent freeze thaw cycles.
Specificity:
Immunoreactive with all sera of HIV-1 and HIV-type O infected individuals and with 60-80% of HIV-2 infected individuals.
Physical Appearance:
Sterile filtered colorless clear solution.